Salmonella enterica serovar Typhimurium expressing mutant lipid A with decreased endotoxicity causes maturation of murine dendritic cells.

@article{Kalupahana2003SalmonellaES,
  title={Salmonella enterica serovar Typhimurium expressing mutant lipid A with decreased endotoxicity causes maturation of murine dendritic cells.},
  author={Ruwani Sagarika Kalupahana and A Romina Emilianus and Duncan J Maskell and Barbara Ann Blacklaws},
  journal={Infection and immunity},
  year={2003},
  volume={71 11},
  pages={6132-40}
}
A major Salmonella component involved in cellular activation is the lipopolysaccharide (LPS) molecule which can act as a dendritic cell (DC) stimulator. The structure of the lipid A domain of the LPS molecule dictates its immunostimulatory capacity with various cell types. In this study, the role of lipid A as an integral component of Salmonella in stimulating murine DCs was studied by using a Salmonella enterica serovar Typhimurium lpxM mutant with defective lipid A. This study revealed that a… CONTINUE READING
Highly Cited
This paper has 17 citations. REVIEW CITATIONS
8 Citations
53 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Similar Papers

Loading similar papers…