Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.

@article{Calverley2007SalmeterolAF,
  title={Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.},
  author={Peter M. A. Calverley and Julie Anne Anderson and Bartolome Celli and Gary Thomas Ferguson and Christine Jenkins and Paul W. Jones and Julie Carol Yates and Joergen Vestbo},
  journal={The New England journal of medicine},
  year={2007},
  volume={356 8},
  pages={775-89}
}
BACKGROUND Long-acting beta-agonists and inhaled corticosteroids are used to treat chronic obstructive pulmonary disease (COPD), but their effect on survival is unknown. METHODS We conducted a randomized, double-blind trial comparing salmeterol at a dose of 50 microg plus fluticasone propionate at a dose of 500 microg twice daily (combination regimen), administered with a single inhaler, with placebo, salmeterol alone, or fluticasone propionate alone for a period of 3 years. The primary… CONTINUE READING
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In - haled corticosteroids and mortality in 7 . 8 . 9 . 10 . 11 . 12 . chronic obstructive pulmonary disease

  • JB Soriano, J Vestbo, NB Pride, V Kiri, C Maden, WC Maier
  • Thorax
  • 2005

A randomized trial comparing lung - volume – reduction surgery with medical therapy for severe emphysema

  • JC Hogg, F Chu, S Utokaparch
  • N Engl J Med
  • 2003

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