Salivary metabolite signatures of oral cancer and leukoplakia.

  title={Salivary metabolite signatures of oral cancer and leukoplakia.},
  author={Jie Wei and Guoxiang Xie and Zengtong Zhou and Peng Shi and Yunping Qiu and Xiaojiao Zheng and Tianlu Chen and Mingming Su and A. Jian-Hua Zhao and Wei Jia},
  journal={International journal of cancer},
  volume={129 9},
Oral cancer, one of the six most common human cancers with an overall 5-year survival rate of <50%, is often not diagnosed until it has reached an advanced stage. The aim of the current study is to explore salivary metabolomics as a disease diagnostic and stratification tool for oral cancer and leukoplakia and evaluate the potential of salivary metabolome for detection of oral squamous cell carcinoma (OSCC). Saliva metabolite profiling for a group of 37 OSCC patients, 32 oral leukoplakia (OLK… CONTINUE READING


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