Salivary lithium concentration--a tool for monitoring psychiatric patients.


Salivary and serum lithium concentrations were measured simultaneously in 118 manic-depressive patients. Lithium concentration in saliva was 2.24 +/- 0.35 times higher than in serum. An equation to calculate serum lithium concentration from salivary measurements was derived: Li serum = 0.36 Li saliva + 0.13. Psychotropic drugs had no effect on the salivary:serum ratio. Eighteen patients were followed for several weeks. A significant correlation coefficient between salivary and serum lithium concentrations was found in thirteen of the eighteen patients studied.


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@article{BenAryeh1980SalivaryLC, title={Salivary lithium concentration--a tool for monitoring psychiatric patients.}, author={H Ben-Aryeh and Hillel Naon and Raymond Szargel and Dikla Gutman and Aya Hefetz}, journal={Oral surgery, oral medicine, and oral pathology}, year={1980}, volume={50 2}, pages={127-9} }