Salivary duct carcinoma: new developments--morphological variants including pure in situ high grade lesions; proposed molecular classification.

@article{Simpson2013SalivaryDC,
  title={Salivary duct carcinoma: new developments--morphological variants including pure in situ high grade lesions; proposed molecular classification.},
  author={Roderick H. W. Simpson},
  journal={Head and neck pathology},
  year={2013},
  volume={7 Suppl 1},
  pages={S48-58}
}
Salivary duct carcinoma (SDC) is an aggressive primary salivary malignancy which microscopically resembles high-grade ductal carcinoma of the breast, with both in situ and invasive patterns. It is typically found in older men, most often in the parotid. It can arise de novo or as the malignant component of carcinoma ex pleomorphic adenoma. SDC is generally a hematoxylin and eosin stain-based diagnosis, with special stains and immunohistochemistry acting mainly in a confirmatory role. Other than… CONTINUE READING