Salivary cytomegalovirus (CMV) shedding, glycoprotein B genotype distribution, and CMV disease in human immunodeficiency virus-seropositive patients.

@article{FidouhHouhou2001SalivaryC,
  title={Salivary cytomegalovirus (CMV) shedding, glycoprotein B genotype distribution, and CMV disease in human immunodeficiency virus-seropositive patients.},
  author={N Fidouh-Houhou and Xavier Duval and François Bissuel and V Bourbonneux and Philippe Flandre and J. L. Ecobichon and Mark C. Jordan and Jean Louis Vild{\'e} and Françoise Brun-V{\'e}zinet and Catherine Leport},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2001},
  volume={33 8},
  pages={1406-11}
}
To assess the frequency of shedding of cytomegalovirus (CMV) in saliva, the distribution of CMV glycoprotein B (gB) genotypes, and the occurrence of CMV diseases, we screened 98 human immunodeficiency virus (HIV)-seropositive patients without CMV disease. CMV was detected by culture more frequently in saliva (45 [46%] of 98 patients) than in blood (7 [7.5%] of 93) and was associated with CD4 cell counts <100 cells/mm3 (P=.013). CMV in the saliva of 37 patients was successfully genotyped. Three… CONTINUE READING

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