Salivary chromogranin A: useful and quantitative biochemical marker of affective state in patients with amyotrophic lateral sclerosis.

@article{Obayashi2008SalivaryCA,
  title={Salivary chromogranin A: useful and quantitative biochemical marker of affective state in patients with amyotrophic lateral sclerosis.},
  author={Konen Obayashi and Kimiko Sato and Rie Shimazaki and Tatsuya Ishikawa and Katsumasa Goto and Hidetsugu Ueyama and Toshihiro Mori and Yasuhiko Ando and Toshihide Kumamoto},
  journal={Internal medicine},
  year={2008},
  volume={47 21},
  pages={
          1875-9
        }
}
OBJECTIVE To evaluate the affective state biochemically and quantitatively in amyotrophic lateral sclerosis (ALS) patients using salivary chromogranin A (CgA) measurement. SUBJECTS AND METHODS Twelve moderate and 12 terminal ALS patients defined using the ALS Health State Scale were studied. The correlation between salivary CgA levels and the 40-item ALS assessment questionnaire (ALSAQ-40) scores was investigated in 12 moderate ALS patients. Moreover, salivary CgA levels in 12 terminal ALS… CONTINUE READING
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