Salivary analysis in oral cancer patients: DNA and protein oxidation, reactive nitrogen species, and antioxidant profile.

@article{Bahar2007SalivaryAI,
  title={Salivary analysis in oral cancer patients: DNA and protein oxidation, reactive nitrogen species, and antioxidant profile.},
  author={Golnar Bahar and Raphael M Feinmesser and Thomas Shpitzer and Aaron Popovtzer and R M Nagler},
  journal={Cancer},
  year={2007},
  volume={109 1},
  pages={
          54-9
        }
}
BACKGROUND Free radicals such as reactive oxygen species (ROS) and reactive nitrogen species (RNS), which induce oxidative and nitrative stress, are main contributors to oral carcinogenesis. The RNS (nitrosamines: nitrates, NO(3), and nitrites, NO(2)) are also produced by the reaction of ROS and other free radicals with nitric oxide (NO) and are therefore in equilibrium with it. METHODS Whole saliva was collected from a group of 25 consenting oral squamous cell carcinoma (OSCC) patients and… CONTINUE READING
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