Salivary Proteins as a Defense Against Dietary Tannins

  title={Salivary Proteins as a Defense Against Dietary Tannins},
  author={T. Shimada},
  journal={Journal of Chemical Ecology},
  • T. Shimada
  • Published 2006
  • Medicine, Biology
  • Journal of Chemical Ecology
  • Tannins, a diverse group of water-soluble phenolics with high affinity to proteins, are widely distributed in various parts of plants, and have negative effects in herbivores after ingestion. Some mammalian species are thought to counteract tannins by secreting tannin-binding salivary proteins (TBSPs). Several types of TBSPs are found in the saliva of laboratory animals, livestock, and wildlife. Among them, proline-rich proteins (PRPs) and histatins are effective precipitators of tannins. It is… CONTINUE READING
    315 Citations

    Paper Mentions

    No Major Role for Binding by Salivary Proteins as a Defense Against Dietary Tannins in Mediterranean Goats
    • 28
    • Highly Influenced
    Tannins in plant-herbivore interactions.
    • 438
    Salivary tannin‐binding proteins are a pervasive strategy used by the folivorous/frugivorous black howler monkey
    • 6
    • PDF
    Howler Monkeys (Alouatta palliata mexicana) Produce Tannin-Binding Salivary Proteins
    • 7
    • PDF
    Effect of condensed tannin ingestion in sheep and goat parotid saliva proteome.
    • 44
    • PDF
    Changes in mouse whole saliva soluble proteome induced by tannin-enriched diet
    • 46
    • PDF
    Saliva of the graminivorous Theropithecus gelada lacks proline‐rich proteins and tannin‐binding capacity
    • 33


    Interaction of plant polyphenols with salivary proteins.
    • A. Bennick
    • Biology, Medicine
    • Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists
    • 2002
    • 370
    • Highly Influential
    • PDF
    Interaction of tannin with human salivary proline-rich proteins.
    • 218
    • Highly Influential
    Binding affinity of hydrolyzable tannins to parotid saliva and to proline-rich proteins derived from it.
    • 91
    Salivary proline-rich proteins in mammals: Roles in oral homeostasis and counteracting dietary tannin
    • 83
    • Highly Influential
    Defense against dietary tannin in herbivores : a survey for proline rich salivary proteins in mammals
    • 83
    • Highly Influential
    Herbivores and Plant Tannins
    • 339
    Do Salivary Proline-Rich Proteins Counteract Dietary Hydrolyzable Tannin in Laboratory Rats?
    • 53
    • Highly Influential
    • PDF
    Tannin-binding proteins in saliva of deer and their absence in saliva of sheep and cattle
    • 182
    • Highly Influential