Saliva substitutes for the treatment of radiation-induced xerostomia—a review

  title={Saliva substitutes for the treatment of radiation-induced xerostomia—a review},
  author={Sebastian Hahnel and Michael Behr and Gerhard Handel and R B{\"u}rgers},
  journal={Supportive Care in Cancer},
The aim of this review is to summarize the in vitro and in vivo evidence on the performance of contemporary saliva substitutes in the treatment of xerostomia and hyposalivation caused by radiation therapy for head and neck malignancies. A literature search was conducted during July to September 2008 in PubMed, using the query terms “saliva substitute”, “saliva substitute and xerostomia”, “artificial saliva”, and “artificial saliva and xerostomia”; for clinical studies, only studies in patients… CONTINUE READING
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