Saliva induces expression of antimicrobial peptides and promotes intracellular killing of bacteria in keratinocytes by epidermal growth factor receptor transactivation.

@article{Mohanty2017SalivaIE,
  title={Saliva induces expression of antimicrobial peptides and promotes intracellular killing of bacteria in keratinocytes by epidermal growth factor receptor transactivation.},
  author={Tirthankar Mohanty and Per Alberius and Artur Schmidtchen and Karina Reiss and J M Schr{\"o}der and Ole E S\orensen},
  journal={The British journal of dermatology},
  year={2017},
  volume={176 2},
  pages={403-412}
}
BACKGROUND Wounds in the oral cavity, constantly exposed to both saliva and bacteria, heal quickly without infection. Furthermore, during licking of skin wounds, saliva promotes wound healing and plays a role in keeping the wound free of infection. OBJECTIVES To investigate whether saliva induces expression of antimicrobial peptides (AMPs) in human epidermal keratinocytes and whether saliva promotes clearance of intracellular bacteria in these cells. METHODS Expression of AMPs was… CONTINUE READING
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