Saliva and bloodspot cortisol: novel sampling methods to assess hydrocortisone replacement therapy in hypoadrenal patients.

@article{Wong2004SalivaAB,
  title={Saliva and bloodspot cortisol: novel sampling methods to assess hydrocortisone replacement therapy in hypoadrenal patients.},
  author={Vincent W Wong and Tony Qi Yan and Andrew Donald and Mark McLean},
  journal={Clinical endocrinology},
  year={2004},
  volume={61 1},
  pages={131-7}
}
BACKGROUND In patients with hypoadrenalism, it is often difficult to assess the optimal dose of glucocorticoid replacement. Serial serum cortisol measurements for a cortisol day curve are sometimes used, but this has low acceptability for patients. In this study, we evaluate the reliability of saliva and capillary bloodspot cortisol as alternative methods in assessing cortisol profiles in hypoadrenal patients on hydrocortisone replacement. METHODS We first examined the correlations between… CONTINUE READING