Saline irrigation for chronic rhinosinusitis.

@article{Chong2016SalineIF,
  title={Saline irrigation for chronic rhinosinusitis.},
  author={Lee Yee Chong and Karen Head and Claire Hopkins and Carl Martin Philpott and Simon Glew and Glenis K. Scadding and Martin J. Burton and Anne G M Schilder},
  journal={The Cochrane database of systematic reviews},
  year={2016},
  volume={4},
  pages={
          CD011995
        }
}
BACKGROUND This review is one of six looking at the primary medical management options for patients with chronic rhinosinusitis.Chronic rhinosinusitis is common and is characterised by inflammation of the lining of the nose and paranasal sinuses leading to nasal blockage, nasal discharge, facial pressure/pain and loss of sense of smell. The condition can occur with or without nasal polyps. Nasal saline irrigation is commonly used to improve patient symptoms. OBJECTIVES To evaluate the effects… 

Figures from this paper

Systemic and topical antibiotics for chronic rhinosinusitis.

The primary outcomes were disease-specific health-related quality of life (HRQL), patient-reported disease severity and the commonest adverse event - gastrointestinal disturbance and it is very uncertain if antibiotics were associated with an increase in gastrointestinal disturbances.

Different types of intranasal steroids for chronic rhinosinusitis.

Low quality evidence was found relating to disease severity and nasal polyps size, with results from the high-dose and low-dose groups being similar and the primary adverse effect, epistaxis, was more common when higher doses were used.

Short-course oral steroids alone for chronic rhinosinusitis.

The results at the end of treatment showed an improvement in patients receiving oral steroids compared to placebo, both when presented as a mean final value and as a change from baseline, which corresponds to a large effect size.

Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis.

The effects of intranasal corticosteroids in people with chronic rhinosinusitis were assessed, disease-specific health-related quality of life (HRQL), patient-reported disease severity and the commonest adverse event - epistaxis.

Topical and systemic antifungal therapy for chronic rhinosinusitis.

The main outcomes were disease-specific health-related quality of life, patient-reported disease severity and the significant adverse effects of hepatic toxicity (systemic antifungals), and the quality of the evidence for each outcome.

Biologics for chronic rhinosinusitis.

This living systematic review is one of several Cochrane Reviews evaluating the medical management of patients with chronic rhinosinusitis and three biologics, with different targets, were evaluated: dupilumab, mepolizumAB and omalizumab.

Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis.

A short course of oral corticosteroids as an adjunct ('add-on') therapy in people with chronic rhinosinusitis who are already on standard treatments and there was a greater improvement in symptom severity 30 days after the start of treatment in patients who received oral steroids and antibiotics.

Saline irrigation for allergic rhinitis.

Saline irrigation may improve patient-reported disease severity compared with no saline at up to four weeks and up to three months, and the evidence was low quality the SMD values at both time points are considered large effect sizes.

Saline nasal irrigations for chronic rhinosinusitis: From everyday practice to evidence-based medicine. An update

The aim of this article is to review the published literature regarding all of the potential therapeutic effects of SNIs in adult CRS patients who had not undergone sinus surgery and clarify the role of the various saline nasal solutions and protocols (particularly the volume, frequency and duration of treatment).
...

References

SHOWING 1-10 OF 67 REFERENCES

Systemic and topical antibiotics for chronic rhinosinusitis.

The primary outcomes were disease-specific health-related quality of life (HRQL), patient-reported disease severity and the commonest adverse event - gastrointestinal disturbance and it is very uncertain if antibiotics were associated with an increase in gastrointestinal disturbances.

Different types of intranasal steroids for chronic rhinosinusitis.

Low quality evidence was found relating to disease severity and nasal polyps size, with results from the high-dose and low-dose groups being similar and the primary adverse effect, epistaxis, was more common when higher doses were used.

Short-course oral steroids alone for chronic rhinosinusitis.

The results at the end of treatment showed an improvement in patients receiving oral steroids compared to placebo, both when presented as a mean final value and as a change from baseline, which corresponds to a large effect size.

Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis.

The effects of intranasal corticosteroids in people with chronic rhinosinusitis were assessed, disease-specific health-related quality of life (HRQL), patient-reported disease severity and the commonest adverse event - epistaxis.

Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis.

A short course of oral corticosteroids as an adjunct ('add-on') therapy in people with chronic rhinosinusitis who are already on standard treatments and there was a greater improvement in symptom severity 30 days after the start of treatment in patients who received oral steroids and antibiotics.

Hyaluronan in the Treatment of Chronic Rhinosinusitis with Nasal Polyposis

HA, as a nebulized nasal douche preparation, improved nasal symptoms and endoscopic appearances in patients with CRS and NP who have not undergone sinus surgery are evaluated.

The Efficacy of Hypertonic Saline Nasal Irrigation for Chronic Sinonasal Symptoms

Hypersaline nasal irrigation in children with symptomatic seasonal allergic rhinitis: A randomized study

This study supports the use of nasal irrigation with hypertonic saline in the pediatric patient with seasonal allergic rhinitis during the pollen season, which was tolerable, inexpensive and effective.

Nasal Irrigation for the Alleviation of Sinonasal Symptoms

Daily nasal irrigation using either a bulb syringe, nasal irrigation pot, and daily reflexology massage were equally efficacious and resulted in improvement in the symptoms of chronic sinusitis in over 70% of subjects.

Effect of irrigation of the nose with isotonic salt solution on adult patients with chronic paranasal sinus disease

Endonasal irrigations with salt solutions are effective in the treatment of chronic sinusitis, and a significant difference between Ems salt and sodium chloride was not observed.
...