Salicylic acid is an uncoupler and inhibitor of mitochondrial electron transport.

@article{Norman2004SalicylicAI,
  title={Salicylic acid is an uncoupler and inhibitor of mitochondrial electron transport.},
  author={Christel Norman and Katharine A Howell and A. Harvey Millar and James M Whelan and David A Day},
  journal={Plant physiology},
  year={2004},
  volume={134 1},
  pages={492-501}
}
The effect of salicylic acid (SA) on respiration and mitochondrial function was examined in tobacco (Nicotiana tabacum) suspension cell cultures in the range of 0.01 to 5 mm. Cells rapidly accumulated SA up to 10-fold of the externally applied concentrations. At the lower concentrations, SA accumulation was transitory. When applied at 0.1 mm or less, SA stimulated respiration of whole cells and isolated mitochondria in the absence of added ADP, indicating uncoupling of respiration. However, at… CONTINUE READING
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