Salicylate impacts the physiological responses to an acute handling disturbance in rainbow trout.

@article{Gravel2007SalicylateIT,
  title={Salicylate impacts the physiological responses to an acute handling disturbance in rainbow trout.},
  author={Am{\'e}lie Gravel and Mathilakath M Vijayan},
  journal={Aquatic toxicology},
  year={2007},
  volume={85 2},
  pages={87-95}
}
While salicylates (non-steroidal anti-inflammatory drugs) have been detected in the aquatic environment, few studies have focused on the mechanism of action of these pharmaceuticals on aquatic organisms. We reported previously that salicylate disrupted the acute trophic hormone-stimulated corticosteroidogenesis in rainbow trout (Oncorhynchus mykiss) interrenal tissue in vitro. Here, we tested the hypothesis that this drug will inhibit the adaptive plasma cortisol response and the associated… CONTINUE READING

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