Salicylate-Functionalized Bismuth Oxido Clusters: Hydrolysis Processes and Microbiological Activity

  title={Salicylate-Functionalized Bismuth Oxido Clusters: Hydrolysis Processes and Microbiological Activity},
  author={Maik Schlesinger and Amita Pathak and Sebasti{\'a}n Richter and Dominik Sattler and Andreas Seifert and Tobias R{\"u}ffer and Philip C. Andrews and Christoph A. Schalley and Heinrich Lang and Michael Mehring},
  journal={European Journal of Inorganic Chemistry},
Hydrolysis of either Bi(HSal4Me)3 (A) or [Bi22O26(HSal4Me)14](B) in dmso gave the 4-methylsalicylate-substituted bismuth oxido cluster [Bi38O45(HSal4Me)24(dmso)14(H2O)2]·4H2O (1·4H2O), which crystallizes in the triclinic space group P with cell parameters of a = 20.7214(5), b = 20.9654(6), c = 22.2128(6) A, α = 100.867(2), β = 114.108(2), γ = 107.895(2)° and V = 7815.1(4) A3. The hydrolysis of A was studied by using 1H DOSY NMR spectroscopy and electrospray ionization Fourier-transform ion… Expand
16 Citations
From a Cerium-Doped Polynuclear Bismuth Oxido Cluster to β-Bi2O3:Ce.
Diffuse-reflectance UV-vis and X-ray photoelectron spectroscopy reveal the presence of CeIV in the final bismuth oxido clusters as a result of oxidation of the cerium source. Expand
The Unexpected Isolation of Bismuth Tris(carboxylate) Hydrates: Syntheses and Structures of [Bi(Hsal)3(H2O)] and [Bi(Hanth)3(H2O)] (H2sal = 2‐OH‐C6H4CO2H, Hanth = 2‐NH2‐C6H4CO2H)
A complex of the composition [Bi(2-OH-C6H4CO2)3(H2O)] (1) was isolated from the 1:3 reaction of BiPh3 with H2sal (H2sal = salicylic acid = 2-OH-C6H4CO2H) in wet xylene, and the analogous anthranilateExpand
Homo- and Heteroleptic Coordination Polymers and Oxido Clusters of Bismuth(III) Vinylsulfonates.
The synthesis and characterization of six homo- and heteroleptic coordination polymers and oxido clusters of bismuth(III) vinylsulfonates are reported. The solvent-mediated reaction of BiPh3 andExpand
Assembling anionic Sb(V)/(III) containing polyoxostibonates stabilized by triphenyltellurium cations.
Interestingly, during the assembly of these POMs several processes happen simultaneously, and the formation of triphenyltellurium cations which not only provide charge balance but also stabilize the POM framework by weak interactions are reported. Expand
Bismuth(III) benzohydroxamates: powerful anti-bacterial activity against Helicobacter pylori and hydrolysis to a unique Bi34 oxido-cluster [Bi34O22(BHA)22(H-BHA)14(DMSO)6].
Reaction of BiPh3 or Bi(O(t)Bu)3 with benzohydroxamic acid results in formation of novel mono- and di-anionic hydroxamato complexes, all of which display nM activity against Helicobacter pylori. Expand
Bismuth(III) complexes derived from α-amino acids: the impact of hydrolysis and oxido-cluster formation on their activity against Helicobacter pylori.
The results of the bactericidal studies against Helicobacter pylori demonstrate that this hydrolysis process impacts significantly on the observed Minimum Inhibitory Concentration (MICs) which are increased substantially, often by many orders of magnitude, when the complexes are initially prepared in water rather than DMSO. Expand
Anionic Bismuth-Oxido Carboxylate Clusters with Transition Metal Countercations.
These are among the first bismuth-oxido anionic clusters synthesized, and the first to have transition metal countercations, and two of the new Bi4O2 clusters are arranged in 1D polymeric structures via bridging carboxylate ligands. Expand
Investigations on the growth of bismuth oxido clusters and the nucleation to give metastable bismuth oxide modifications
Abstract Investigations on bismuth oxido clusters are focused on the nucleation and growth processes towards large cluster motifs and their stability in the gas phase, which has been studied byExpand
Structural Insights into New Bi(III) Coordination Polymers with Pyridine-2,3-Dicarboxylic Acid: Photoluminescence Properties and Anti-Helicobacter pylori Activity
It can be concluded that there is an existing relationship between the structure and the antibacterial activity because the presence of chloride and triethylammonium ions in the structure of complex 2 reduces the antib bacterial activity. Expand
Hydrolysis Mechanism of Bismuth in Chlorine Salt System Calculated by Density Functional Method
Based on the density functional theory, this paper presents the calculated cellular electronic properties of BiCl3, BiOCl and Bi3O4Cl, including unit cell energy, band structure, total density ofExpand


Nanoscaled Bismuth Oxido Clusters: Probing Factors of Structure Formation and Photocatalytic Activity
Hydrolysis of bismuth(III) nitrate in the presence of sodium benzoate (NaOBz) in dimethyl sulfoxide (DMSO) gave the bismuth oxido clusterExpand
Solvent-free synthesis of bismuth thiolates and carboxylates
The thermally induced solvent-free reactions of Ph3Bi with a series of thiols and carboxylic acids (2-mercaptobenzothiazole, 2-mercaptobenzoxazole, 2-ethoxybenzoic acid, 1-mercapto-2-propanol andExpand
Hydrolysis of a basic bismuth nitrate--formation and stability of novel bismuth oxido clusters.
Examination of the fragmentation pathways of 1a and 2 by infrared multi-photon dissociation (IRMPD) tandem MS experiments allows the identification of novel bismuth oxido cluster species in the gas phase. Expand
Fluorinated bismuth alkoxides: from monomers to polymers and oxo-clusters.
Structural analyses reveal that under variable reaction conditions the interaction of BiAr3 with (CF3)2CHOH can give a mixture of bismuth complexes with varying degrees of substitution, cluster formation and aggregation. Expand
From {Bi22O26} to chiral ligand-protected {Bi38O45}-based bismuth oxido clusters.
The reaction of [Bi(22)O(26)(OSiMe(2)tBu)(14)] (1) in THF with salicylic acid gave [Bi(22)O(24)(HSal)(14)] (2) first, which was converted into [Bi(38)O(45)(HSal)(22)(OH)(2)(DMSO)(16.5)]·DMSO·H(2)OExpand
Synthesis and Characterization of New Phenylbis(salicylato)bismuth(III) Complexes
Compounds with the compositions [BiPh(Hsal)2] (1a) and [BiPh(Hsal4Me)2] (1b) were prepared by the reactions of triphenylbismuth with 2-hydroxybenzoic acid (H2sal) and 4-methyl-2-hydroxybenzoic acidExpand
Hydrolysis studies on bismuth nitrate: synthesis and crystallization of four novel polynuclear basic bismuth nitrates.
Variation of the conditions for partial hydrolysis of Bi(NO(3))(3) gave bismuth oxido nitrates of even higher nuclearity, and differences in the number of DMSO molecules (coordinated and noncoordinated) and ligand (nitrate, D MSO) coordination modes are observed. Expand
Bi38 Oxocarboxylate Cages are Keplerates – Synthesis and Structural Characterization of Two Bi38 Oxocarboxylate Cages
The reaction of 3,5-dinitrobenzenecarboxylic acid with triphenylbismuth in a 1:1 stoichiometric ratio in toluene under reflux afforded two new Bi38 oxocarboxylate cagesExpand
Hydrothermal synthesis of two cationic bismuthate clusters: an alkylenedisulfonate bridged hexamer, [Bi6O4(OH)4(H2O)2][(CH2)2(SO3)2]3 and a rare nonamer templated by triflate, [Bi9O8(OH)6][CF3SO3]5.
The synthesis, characterization, and application of two cationic bismuthate clusters by anion templating demonstrate the use of sulfonate groups for the anion-directed assembly of these rare cationsic inorganic structures. Expand
Structural and solution studies of phenylbismuth(III) sulfonate complexes and their activity against Helicobacter pylori.
The presence of the single sulfonato ligand in compounds 1, 2 and 3 resulted in a dramatic increase in bacteriocidial activity towards H. pylori (MIC values of ≥6.25 μg mL (-1)) relative to BiPh(3) (>64 μg mL(-1)) and the sulfonic acids, which were essentially inactive. Expand