Saitohin polymorphism and executive dysfunction in schizophrenia

  title={Saitohin polymorphism and executive dysfunction in schizophrenia},
  author={Marta Bosia and Mariachiara Buonocore and Carmelo Guglielmino and Adele Pirovano and Cristina Lorenzi and Alessandra Marcone and Placido Bramanti and Stefano F. Cappa and Eugenio Aguglia and Enrico Smeraldi and Roberto Cavallaro},
  journal={Neurological Sciences},
Saitohin (STH) is an intronless gene nested within the human tau gene, which contains a single nucleotide polymorphism (A/G), suggested to be involved in the physiopathology and clinical course of several neurodegenerative and neuropsychiatric diseases. Recently, an association between this polymorphism and frontal hypoperfusion and clinical prognosis in frontotemporal dementia was reported. The present study sought to evaluate the possible role of the STH polymorphism as a concurring factor of… CONTINUE READING