Saitohin, which is nested within the tau gene, interacts with tau and Abl and its human-specific allele influences Abl phosphorylation.

@article{Wang2011SaitohinWI,
  title={Saitohin, which is nested within the tau gene, interacts with tau and Abl and its human-specific allele influences Abl phosphorylation.},
  author={Yan Wang and Lei Gao and Christopher G Conrad and A. Harriette Andreadis},
  journal={Journal of cellular biochemistry},
  year={2011},
  volume={112 11},
  pages={
          3482-8
        }
}
Saitohin (STH) is a gene unique to humans and their closest relatives whose function is not yet known. STH contains a single polymorphism (Q7R); the Q allele is human-specific and confers susceptibility to several neurodegenerative diseases. In previous work, we discovered that STH interacts with Peroxiredoxin 6 (Prdx6), a unique member of that family which is bifunctional and whose levels increase in Pick's disease. In this study, we report that STH also interacts with tau and the non-receptor… CONTINUE READING
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