Safranal ameliorates antioxidant enzymes and suppresses lipid peroxidation and nitric oxide formation in aged male rat liver

@article{Farahmand2012SafranalAA,
  title={Safranal ameliorates antioxidant enzymes and suppresses lipid peroxidation and nitric oxide formation in aged male rat liver},
  author={Seyed Kazem Farahmand and Fariborz Samini and Mohammad Samini and Saeed Samarghandian},
  journal={Biogerontology},
  year={2012},
  volume={14},
  pages={63-71}
}
Free radical production and oxidative stress are known to increase in liver during aging, and may contribute to oxidative damage. The objective of this study was to observe the changes in activities of antioxidant enzymes (superoxide dismutase, glutathione-S-transferase, catalase), lipid peroxidation levels and serum nitric oxide occurring in livers of rats of 2, 10 and 20 months old, and to see whether these changes are restored to those of the two month old control levels rats after… CONTINUE READING
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