Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action
@article{Lopresti2014SaffronS, title={Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action}, author={Adrian L Lopresti and P. Drummond}, journal={Human Psychopharmacology: Clinical and Experimental}, year={2014}, volume={29}, pages={517 - 527} }
BACKGROUND
Saffron, a spice derived from the flower of Crocus sativus, has now undergone several trials examining its antidepressant effects and, in a recent meta-analysis, was confirmed to be effective for the treatment of major depression. [...] Key MethodDESIGN
In the systematic review of clinical trials, electronic databases were searched for high-quality, randomised, double-blind studies, with placebo or antidepressant controls.Expand Abstract
Topics from this paper
Paper Mentions
89 Citations
A placebo controlled randomized clinical trial of Crocus sativus L. (saffron) on depression and food craving among overweight women with mild to moderate depression
- Medicine
- Journal of clinical pharmacy and therapeutics
- 2019
- 1
The efficacy of Crocus sativus (Saffron) versus placebo and Fluoxetine in treating depression: a systematic review and meta-analysis
- Medicine
- Psychology research and behavior management
- 2019
- 3
- PDF
Safety and Efficacy of Saffron (Crocus sativus L.) for Treating Mild to Moderate Depression
- Medicine
- The Journal of nervous and mental disease
- 2020
- 1
Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis.
- Medicine
- Nutrition reviews
- 2019
- 11
- PDF
Antianhedonic and Antidepressant Effects of Affron®, a Standardized Saffron (Crocus Sativus L.) Extract
- Medicine
- Molecules
- 2020
- PDF
Nutritional and health beneficial properties of saffron (Crocus sativus L): a comprehensive review.
- Biology, Medicine
- Critical reviews in food science and nutrition
- 2020
Crocus sativus L. versus Citalopram in the Treatment of Major Depressive Disorder with Anxious Distress: A Double-Blind, Controlled Clinical Trial.
- Psychology, Medicine
- Pharmacopsychiatry
- 2017
- 33
- PDF
affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial.
- Medicine
- Complementary therapies in medicine
- 2017
- 19
- PDF
Efficacy of Crocus sativus (saffron) in treatment of major depressive disorder associated with post-menopausal hot flashes: a double-blind, randomized, placebo-controlled trial
- Medicine
- Archives of Gynecology and Obstetrics
- 2018
- 16
References
SHOWING 1-10 OF 107 REFERENCES
Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double‐blind, randomised and placebo‐controlled trial
- Medicine
- BJOG : an international journal of obstetrics and gynaecology
- 2008
- 153
- PDF
Saffron (Crocus sativus L.) and major depressive disorder: a meta-analysis of randomized clinical trials.
- Medicine
- Journal of integrative medicine
- 2013
- 77
- Highly Influential
- PDF
Saffron for treatment of fluoxetine‐induced sexual dysfunction in women: randomized double‐blind placebo‐controlled study
- Psychology, Medicine
- Human psychopharmacology
- 2013
- 76
Crocus sativus L. in the treatment of mild to moderate depression: a double‐blind, randomized and placebo‐controlled trial
- Medicine
- Phytotherapy research : PTR
- 2005
- 249
- Highly Influential
- PDF
ANTIDEPRESSANT EFFECT OF KAEMPFEROL, A CONSTITUENT OF SAFFRON (CROCUS SATIVUS) PETAL, IN MICE AND RATS
- Biology
- 2007
- 64
- PDF
Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial.
- Medicine
- Journal of ethnopharmacology
- 2005
- 223
- Highly Influential
Saffron in the treatment of patients with mild to moderate Alzheimer’s disease: a 16‐week, randomized and placebo‐controlled trial
- Medicine
- Journal of clinical pharmacy and therapeutics
- 2010
- 145
- PDF
Petal and Stigma of Crocus sativus L. in the Treatment of Depression: A Pilot Double - blind Randomized Trial
- Medicine
- 2008
- 32
- PDF
Anti-inflammatory properties of drugs from saffron crocus.
- Biology, Medicine
- Anti-inflammatory & anti-allergy agents in medicinal chemistry
- 2012
- 76