Safety profile of conjugated linoleic acid in a 12-month trial in obese humans.

  title={Safety profile of conjugated linoleic acid in a 12-month trial in obese humans.},
  author={Leah D. Whigham and Marianne O'Shea and Inge C. M. Mohede and Heidi P Walaski and Richard L Atkinson},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  volume={42 10},
Conjugated linoleic acid (CLA) is marketed in numerous commercially available dietary supplements, but few studies have looked at the long-term safety of this product. The current study evaluated the safety of one CLA product (Clarinol) over a one-year period in obese humans who were generally healthy. This was a randomized, double-blind study consisting of three phases in which subjects were given 6 g/day of CLA or placebo. Phase 1 was a low calorie diet (13 kcal/kg desirable weight) for 12… CONTINUE READING

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Effects of two conjugated linoleic acid isomers on body fat mass in overweight humans

  • C. Malpuech-Brugere, W. P. Verboeket-van de Venne, +8 authors B. Beaufrere
  • Obes. Res
  • 2004
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