Safety of treatment with DLA-identical or unrelated mesenchymal stromal cells in DLA-identical canine bone marrow transplantation.

@article{Kornblit2013SafetyOT,
  title={Safety of treatment with DLA-identical or unrelated mesenchymal stromal cells in DLA-identical canine bone marrow transplantation.},
  author={Brian Thomas Kornblit and Wendy M Leisenring and E. B. De Los Santos and Rainer F Storb and Brenda M Sandmaier},
  journal={Chimerism},
  year={2013},
  volume={4 3},
  pages={95-101}
}
BACKGROUND Although in vitro and in vivo experiments have suggested that mesenchymal stromal cells (MSC) may have important immunomodulatory functions in allogeneic hematopoietic cell transplantation (HCT), results from clinical studies have been inconsistent. In the current study we investigate the safety of dog leukocyte antigen (DLA) identical or third party unrelated MSC in DLA-identical HCT. RESULTS There were no differences between treatment groups in depth of granulocyte or platelet… CONTINUE READING
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