Safety of transforaminal lumbar interbody fusion and intervertebral recombinant human bone morphogenetic protein-2.

@article{Villavicencio2005SafetyOT,
  title={Safety of transforaminal lumbar interbody fusion and intervertebral recombinant human bone morphogenetic protein-2.},
  author={Alan T. Villavicencio and Sigita Burneikiene and Ewell Lee Nelson and Ketan R. Bulsara and Mark Favors and Jeffrey J Thramann},
  journal={Journal of neurosurgery. Spine},
  year={2005},
  volume={3 6},
  pages={436-43}
}
OBJECT Recombinant human bone morphogenetic protein-2 (rhBMP-2) is being increasingly used for spinal fusion. There are few data regarding its clinical safety, effectiveness, and clinical outcome when applied on an absorbable collagen sponge (ACS) in conjunction with allograft for transforaminal lumbar interbody fusion (TLIF). METHODS Seventy-four consecutive patients undergoing TLIF for degenerative disc disease were divided into five groups depending on whether the patient underwent a… CONTINUE READING