Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews.

@article{Cates2012SafetyOR,
  title={Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews.},
  author={Christopher J Cates and Marta Oleszczuk and Elizabeth Stovold and L. Susan Wieland},
  journal={The Cochrane database of systematic reviews},
  year={2012},
  volume={10},
  pages={CD010005}
}
BACKGROUND Two large surveillance studies in adults with asthma have found an increased risk of asthma-related mortality in those who took regular salmeterol as monotherapy in comparison to placebo or regular salbutamol. No similar sized surveillance studies have been carried out in children with asthma, and we remain uncertain about the comparative safety of regular combination therapy with either formoterol or salmeterol in children with asthma. OBJECTIVES We have used the paediatric trial… CONTINUE READING
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Airway hyper-responsiveness as a determinant of the early asthmatic response to inhaled allergen

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