Safety of pertussis vaccination in pregnant women in UK: observational study

  title={Safety of pertussis vaccination in pregnant women in UK: observational study},
  author={Katherine Donegan and Bridget D King and Phil Bryan},
OBJECTIVE To examine the safety of pertussis vaccination in pregnancy. DESIGN Observational cohort study. SETTING The UK Clinical Practice Research Datalink. PARTICIPANTS 20,074 pregnant women with a median age of 30 who received the pertussis vaccine and a matched historical unvaccinated control group. MAIN OUTCOME MEASURE Adverse events identified from clinical diagnoses during pregnancy, with additional data from the matched child record identified through mother-child linkage. The… CONTINUE READING


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