Safety of one 52-mumol (50,000 IU) oral dose of vitamin A administered to neonates.

  title={Safety of one 52-mumol (50,000 IU) oral dose of vitamin A administered to neonates.},
  author={Tina Agoestina and Jean H. Humphrey and George A Taylor and Ahmed Usman and D Subardja and Syarif Hidayat and M Nurachim and Ling-ling Wu and Dara S. Friedman and Keith P West},
  journal={Bulletin of the World Health Organization},
  volume={72 6},
A placebo-controlled trial was carried out among 2067 Indonesian neonates to assess the safety of administering one oral 52-mumol (50,000 IU) dose of vitamin A. Infants were assessed for potential acute side-effects before and throughout 48 hours after the dose. The first 965 infants were examined by cranial ultrasound before and at 24 hours after dosing to rule out intracranial haemorrhage and determine the resistive index (RI) of the anterior cerebral artery using duplex Doppler. Groups were… CONTINUE READING

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