Safety of monoclonal antibodies for the treatment of multiple sclerosis

  title={Safety of monoclonal antibodies for the treatment of multiple sclerosis},
  author={M. McGinley and B. Moss and J. Cohen},
  journal={Expert Opinion on Drug Safety},
  pages={100 - 89}
  • M. McGinley, B. Moss, J. Cohen
  • Published 2017
  • Medicine
  • Expert Opinion on Drug Safety
  • ABSTRACT Introduction: Monoclonal antibodies are a potent therapeutic approach for relapsing-remitting multiple sclerosis. This group of medications comprises diverse mechanisms of action resulting in both shared and unique adverse effects. Areas covered: The major trials and safety profiles of natalizumab, alemtuzumab, daclizumab, rituximab, and ocrelizumab are discussed. While each drug has a unique safety profile, one of the potential safety concerns for all of these drugs is infection… CONTINUE READING
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