Safety of inhalation of a 50% nitrous oxide/oxygen premix: a prospective survey of 35 828 administrations.

@article{Onody2006SafetyOI,
  title={Safety of inhalation of a 50% nitrous oxide/oxygen premix: a prospective survey of 35 828 administrations.},
  author={Peter Onody and P. Rodrı́guez – Gil and Martine Hennequin},
  journal={Drug safety},
  year={2006},
  volume={29 7},
  pages={
          633-40
        }
}
BACKGROUND A 50% nitrous oxide/oxygen (N(2)O/O(2)) premix is widely used to alleviate pain or anxiety during brief care procedures in various medical domains. In some countries, recent changes in regulation status for medical gases state that they should be considered as drugs. Consequently, more valuable data gained from exhaustive clinical surveys are needed. This prospective study, conducted in the same conditions imposed for testing a drug, aims to analyse the factors that affect tolerance… CONTINUE READING

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