Safety of inducing sputum in patients with asthma of varying severity.

  title={Safety of inducing sputum in patients with asthma of varying severity.},
  author={P T de la Fuente and Micaela Romagnoli and Philippe P Godard and Jean Bousquet and Pascal Chanez},
  journal={American journal of respiratory and critical care medicine},
  volume={157 4 Pt 1},
Inducing sputum using hypertonic saline is a noninvasive method to investigate airway inflammation in people with asthma. However, hypertonic saline may also induce bronchoconstriction in some patients. The aim of the study was to examine whether the overall safety of using hypertonic saline to induce sputum in patients with mild to moderate asthma could be extended to patients with severe and/or uncontrolled asthma. Nine control subjects and 64 asthmatic patients with varying severity of the… CONTINUE READING
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