Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis

@article{Ford2014SafetyOE,
  title={Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis},
  author={N. Ford and L. Mofenson and Z. Shubber and A. Calmy and I. Andrieux-Meyer and M. Vit{\'o}ria and N. Shaffer and F. Renaud},
  journal={AIDS},
  year={2014},
  volume={28},
  pages={S123–S131}
}
  • N. Ford, L. Mofenson, +5 authors F. Renaud
  • Published 2014
  • Medicine
  • AIDS
  • Introduction:Primate studies and some observational human data have raised concern regarding an association of first-trimester efavirenz exposure with central nervous system congenital anomalies. The objective of this review is to update evidence on efavirenz safety in HIV-infected pregnant women to inform revision of the 2013 WHO guidelines for antiretroviral therapy in low and middle-income countries. Design:A systematic review and meta-analysis. Methods:We searched for studies reporting… CONTINUE READING
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