Safety of ciprofloxacin in children: Worldwide clinical experience based on compassionate use. Emphasis on joint evaluation

@article{Chysk1991SafetyOC,
  title={Safety of ciprofloxacin in children: Worldwide clinical experience based on compassionate use. Emphasis on joint evaluation},
  author={Dr. vet. med. V. Chysk{\'y} and Dipl.-Psych. R. Hullmann and Dr. med. vet. P. Schacht and Kusum Kapila and Roger Echols and G P Arcieri},
  journal={Infection},
  year={1991},
  volume={19},
  pages={289-296}
}
Six hundred and thirty four adolescents and children aged three days to 17 years treated with ciprofloxacin on a compassionate basis were analysed for drug safety. 62% of the ciprofloxacin courses were given to patients with respiratory tract infection, primarily those with acute pulmonary exacerbation of cystic fibrosis. The mean daily oral dose was 25.2 mg/kg body weight. The duration of treatment ranged from one to 880 days (mean 22.8 days). Because of the arthropathogenic potential of… CONTINUE READING

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