Safety of caspofungin for treating invasive nasal sinus aspergillosis in a kidney transplant recipient.

@article{Said2005SafetyOC,
  title={Safety of caspofungin for treating invasive nasal sinus aspergillosis in a kidney transplant recipient.},
  author={Tarek Said and Mangalathillam R N Nampoory and M G Prabhachandran Nair and Mervat Al-Saleh and K H Al-Haj and Medhat Abdel Halim and Kaivilayil V. Johny and Mahmoud Samhan and Mostafa Al-Mousawi},
  journal={Transplantation proceedings},
  year={2005},
  volume={37 7},
  pages={3038-40}
}
INTRODUCTION Invasive fungal sinusitis is a rare but often fatal infection in immunocompromised patients. Aggressive antifungal treatment is mandatory, but is not without risk. Caspofungin, an antifungal agent that is a member of the echinocandin family, an inhibitor of glucan synthesis in the fungal wall, is active against Aspergillus and Candidae infections. Although it works on the fungal wall, it does not affect mammalian cells; hence, its toxicity is minimal. CASE SUMMARY This report… CONTINUE READING