Safety of ACE inhibitor therapies in patients with chronic kidney disease

@article{Sidorenkov2014SafetyOA,
  title={Safety of ACE inhibitor therapies in patients with chronic kidney disease},
  author={Grigory Sidorenkov and Gerjan J Navis},
  journal={Expert Opinion on Drug Safety},
  year={2014},
  volume={13},
  pages={1383 - 1395}
}
Introduction: ACE inhibitors are first-line therapy in patients with chronic kidney disease (CKD). The main adverse effects of ACE inhibitors are hypotension, renal function impairment and hyperkalemia. Areas covered: This paper reviews evidence from clinical studies regarding adverse effects of ACE inhibitors in patients with CKD. The safety aspects of ACE inhibitors are discussed in relation to their pharmacological action, drug–drug interactions, drug–diet interaction, precautions needed in… 
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