Safety margin at single neuromuscular junctions.

  title={Safety margin at single neuromuscular junctions.},
  author={Jo{\vz}e V. Trontelj and Marjan Mihelin and Adnan J. Khuraibet},
  journal={Muscle & nerve. Supplement},
Jitter measurement with axonal microstimulation was used to study synaptic function at 115 neuromuscular junctions (NMJs) of normal subjects at various stimulation rates. Jitter was lowest at 0.5 Hz; it increased slightly at 1, 2, and 5 Hz and remained at that level at 10 Hz (a light work load) and 20 Hz (a heavy work load); and it increased further at 50 Hz (an extreme load). This pattern was seen for the majority of the NMJs, suggesting a high safety factor of neuromuscular transmission… CONTINUE READING