Safety follow-up in a cohort of Biken acellular DPT vaccine recipients in Japan.

@article{Chazono1991SafetyFI,
  title={Safety follow-up in a cohort of Biken acellular DPT vaccine recipients in Japan.},
  author={M Chazono and Tetsuya Hirota and Isao Yoshida and T Konobe and Kazuaki Takaku and Kanji Fukai},
  journal={Developments in biological standardization},
  year={1991},
  volume={73},
  pages={323-7}
}
In October 1984 in Sweden, a phase II trial of Biken acellular Pertussis vaccine was started and in 1986, a phase III trial of the same vaccine was begun. During the phase III trial, there were three cases of deaths out of 1,385 of study children at two, four and ten weeks after the second dose of the vaccine, due to severe invasive bacterial infections… CONTINUE READING