Safety evaluation of repeated intravenous infusion of sinoporphyrin with and without PDT in rats.

@article{Shi2016SafetyEO,
  title={Safety evaluation of repeated intravenous infusion of sinoporphyrin with and without PDT in rats.},
  author={Rui Shi and Xiaoqi Lin and Jingxuan Zhang and Hongtao Jin and Aiping Wang and Jinfeng Wei},
  journal={Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology},
  year={2016},
  volume={15 11},
  pages={1366-1376}
}
Photodynamic therapy (PDT) is a promising antineoplastic modality in the oncology field. We assessed the safety of repeated intravenous administrations of sinoporphyrin, a porphyrin derivative, with and without illumination in rats. Toxicokinetic studies of single and multiple administrations of sinoporphyrin were also carried out. Sprague-Dawley rats were… CONTINUE READING