Safety evaluation of Trikatu, a generic Ayurvedic medicine in Charles Foster rats.

  title={Safety evaluation of Trikatu, a generic Ayurvedic medicine in Charles Foster rats.},
  author={Debabrata Chanda and Karuna Shanker and Anirban Pal and Suaib Luqman and Dnyaneshwar Umrao Bawankule and Dayanandan Mani and Mahendra Pandurang Darokar},
  journal={The Journal of toxicological sciences},
  volume={34 1},
Chemical characterization and acute and sub-acute toxicity study of Trikatu, a generic herbal formulation of Indian system of medicine, was carried out in Charles Foster (CF) rats for safety profiling. In acute toxicity experiment, Trikatu at 2,000 mg/kg body weight once orally was well tolerated by the experimental animals (both male and female) and no changes were observed in mortality, morbidity, gross pathology, gain in weight, vital organ weight, hematological (total white blood cells (WBC… 

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