Safety assessment of the calcium-binding protein, apoaequorin, expressed by Escherichia coli.

@article{Moran2014SafetyAO,
  title={Safety assessment of the calcium-binding protein, apoaequorin, expressed by Escherichia coli.},
  author={Daniel L Moran and A. Tetteh and R. Goodman and Mark Y. Underwood},
  journal={Regulatory toxicology and pharmacology : RTP},
  year={2014},
  volume={69 2},
  pages={
          243-9
        }
}
Calcium-binding proteins are ubiquitous modulators of cellular activity and function. Cells possess numerous calcium-binding proteins that regulate calcium concentration in the cytosol by buffering excess free calcium ion. Disturbances in intracellular calcium homeostasis are at the heart of many age-related conditions making these proteins targets for therapeutic intervention. A calcium-binding protein, apoaequorin, has shown potential utility in a broad spectrum of applications for human… Expand
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