Safety assessment of essential oil from Minthostachys verticillata (Griseb.) Epling (peperina): 90-days oral subchronic toxicity study in rats.

@article{Escobar2015SafetyAO,
  title={Safety assessment of essential oil from Minthostachys verticillata (Griseb.) Epling (peperina): 90-days oral subchronic toxicity study in rats.},
  author={Franco Mat{\'i}as Escobar and Mar{\'i}a Carola Sabini and Laura Noelia Cariddi and Liliana In{\'e}s Sabini and Fernando Mart{\'i}nez Ma{\~n}as and A Cristofolini and Guillermo Bagnis and Mauro Nicol{\'a}s Gallucci and L R Cavaglieri},
  journal={Regulatory toxicology and pharmacology : RTP},
  year={2015},
  volume={71 1},
  pages={1-7}
}
Minthostachys verticillata (Lamiaceae), popularly known as peperina is largely used in popular medicine for its digestive, carminative, antispasmodic and antirheumatic properties. There are no reports of repeated exposure toxicity to guarantee their safety. The present study investigated the chemical composition, analyzed by GC-FID, and the 90-day toxicity and genotoxicity effect of M. verticillata essential oil (Mv-EO), using Wistar rats as test animals. The rats were divided into four groups… CONTINUE READING