Safety assessment of DHA-rich microalgae from Schizochytrium sp.

  title={Safety assessment of DHA-rich microalgae from Schizochytrium sp.},
  author={Bruce G. Hammond and Dale A Mayhew and Joseph F Holson and Mark D Nemec and Richard W Mast and Wayne J. Sander},
  journal={Regulatory toxicology and pharmacology : RTP},
  volume={33 2},
Schizochytrium sp. (DRM) contains oil rich in highly unsaturated fatty acids (PUFAs). Docosahexaenoic acid (DHA) is the most abundant PUFA component of the oil (approx. 35% w/w). DHA-rich extracted oil from Schizochytrium sp. is intended for use as a nutritional ingredient in foods. As part of a comprehensive safety assessment program, the developmental toxicity of DRM was assessed in Sprague-Dawley derived rats [25/group, provided DRM in the diet at 0.6, 6, and 30% on gestation days (GD) 6-15… CONTINUE READING