Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: a proven reality

@article{Elewski2005SafetyAT,
  title={Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: a proven reality},
  author={B E Elewski and Amir Tavakkol},
  journal={Therapeutics and Clinical Risk Management},
  year={2005},
  volume={1},
  pages={299 - 306}
}
Clinicians now have five oral antifungal therapeutic agents to choose from when assessing the risk-benefits associated with a particular treatment for onychomycosis (OM): griseofulvin, itraconazole, terbinafine, ketoconazole, and fluconazole. Only the first three are approved by the FDA for this indication. Griseofulvin is fungistatic and inhibits nucleic acid synthesis, arresting cell division at metaphase, and impairing fungal wall synthesis. Due to its low cure rates and high relapse, it is… CONTINUE READING
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  • SM Abdel-Rahman, K Marcucci, T Boge
  • Drug Metab Dispos
  • 1999
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