Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

@article{Folegatti2020SafetyAI,
  title={Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial},
  author={Pedro M. Folegatti and Katie J. Ewer and Parvinder K. Aley and Brian Angus and Stephan Becker and Sandra Belij-Rammerstorfer and Duncan Bellamy and Sagida Bibi and Mustapha Bittaye and Elizabeth A. Clutterbuck and Christina Dold and Saul N Faust and Adam Finn and Amy Flaxman and Bassam Hallis and Paul T. Heath and Daniel Jenkin and Rajeka Lazarus and Rebecca A. Makinson and Angela M. Minassian and Katrina M. Pollock and Maheshi N. Ramasamy and Hannah Robinson and Matthew D. Snape and Richard D. R. Tarrant and Merryn Voysey and Catherine M. Green and Alexander D Douglas and Adrian V.S. Hill and Teresa Lambe and Sarah C. Gilbert and Andrew J. Pollard and Jeremy Kelly Aabidah Elizabeth Jennifer L. Rachel Edward Aboagye Adams Ali Allen Allison Anslow Arbe-Barnes and Jeremy Aboagye and Kelly Adams and Aabidah Ali and Elizabeth R. Allen and Jennifer L. Allison and Rachel Anslow and Edward H Arbe-Barnes and Gavin Babbage and Kenneth J. Baillie and Megan Baker and Natalie Baker and Philip Baker and Ioana Baleanu and Juliana Ballaminut and Eleanor J Barnes and Jordan R. Barrett and Louise Bates and Alexander Batten and Kirsten Beadon and Rebecca Beckley and Eleanor Berrie and Lisa Berry and Amy Beveridge and Kevin R. Bewley and Else M Bijker and Tracey Bingham and Luke Blackwell and Caitlin L. Blundell and Emma Bolam and Elena Boland and Nicola J. Borthwick and Thomas R. Bower and Amy C. Boyd and Tanja Brenner and Philip D. Bright and Charlie Brown-O'Sullivan and Emily Brunt and Jamie Burbage and Sharon Burge and Karen Buttigieg and Nicholas Byard and Ingrid Cabera Puig and Anna Calvert and Susana Camara and Michelangelo Cao and Federica Cappuccini and Melanie Carr and Miles W. Carroll and Victoria S. Carter and Katrina Cathie and Ruth Challis and Sue Charlton and Irina Chelysheva and Jee Sun Cho and Paola Cicconi and Liliana Cifuentes and Helen Clark and Elizabeth Clark and Tom Cole and Rachel Colin-Jones and Christopher P. Conlon and Aislinn Cook and Naomi S. Coombes and Rachel Cooper and Catherine A. Cosgrove and Karen Coy and Wendy E.M. Crocker and Christina J. Cunningham and Brad E. Damratoski and Lynne Dando and Mehreen S. Datoo and Hannah Davies and Hans de Graaf and Tesfaye Andualem Demissie and Claudio Di Maso and Isabelle Dietrich and Tao Dong and Francesca R Donnellan and Naomi Douglas and Charlotte Downing and Jonathan Drake and Rachael Drake-Brockman and Ruth Elizabeth Drury and Susanna J . Dunachie and Nick J. Edwards and Frances Edwards and Chris J. Edwards and Sean Elias and Michael J. Elmore and Kate R. Emary and Marcus Rex English and Susanne Fagerbrink and Sally Felle and Shuo Feng and Samantha M. Field and Carine Fixmer and Clare Fletcher and Karen Jackson Ford and Jamie Fowler and Polly Fox and Emma Francis and John Frater and Julie M. Furze and Michelle Fuskova and Eva P. Galiza and Diane Gbesemete and Ciaran Gilbride and Kerry J. Godwin and Giacomo Gorini and Lyndsey Goulston and Caroline Grabau and Lara Gracie and Zoe Gray and Lucy Belle Guthrie and Mark J Hackett and Sandro Halwe and Elizabeth Hamilton and Joseph Hamlyn and Brama Hanumunthadu and Irasha Harding and Stephanie A. Harris and Andrew Harris and Daisy Harrison and Clare Harrison and Thomas C Hart and Louise Haskell and Sophia Hawkins and Ian Head and JohnA. Henry and Jennifer Hill and Susanne H Hodgson and Mimi M. Hou and Elizabeth Howe and Nicola J. Howell and Cecilia Hutlin and Sabina Ikram and Catherine Emily Isitt and Poppy Iveson and Susan A. Jackson and Frederic Jackson and Sir William James and Megan H. Jenkins and Elizabeth Jones and Kathryn L. Jones and Christine Elizabeth Jones and Bryony Jones and Reshma Kailath and Konstantinos Karampatsas and Jade Keen and Sarah Kelly and Dearbhla M. Kelly and David Kerr and Simon A. Kerridge and Liaquat Khan and Uzma Khan and Annabel Killen and Jasmin Kinch and Thomas Butler King and Lloyd D. W. King and Jade King and Lucy Kingham-Page and Paul Klenerman and Francesca Knapper and Julian C. Knight and Daniel Knott and Stanislava Koleva and Alexandra Kupke and Colin W. Larkworthy and Jessica P.J. Larwood and Anna Laskey and Alison M. Lawrie and Arlene Lee and Kim Yee Ngan Lee and Emily A Lees and Helen Legge and Alice Lelliott and Nana-Marie Lemm and Amelia M Lias and Aline Linder and Samuel Lipworth and Xinxue Liu and Shuchang Liu and Raquel Lopez Ramon and May Nwe Lwin and Francesca Mabesa and Meera Madhavan and Garry Mallett and Kushal Mansatta and In{\^e}s Filipa Marçal and Spyridoula Marinou and Emma L. Marlow and Julia L. Marshall and Jane Martin and Joanne Mcewan and Lorna McInroy and Gretchen Meddaugh and Alexander J. Mentzer and Neginsadat Mirtorabi and Maria Moore and Edward Moran and Ella Morey and Victoria Morgan and Susan J. Morris and Hazel Morrison and Gertraud Morshead and Richard Morter and Yama F. Mujadidi and Jilly Muller and Tatiana Múnera-Huertas and Claire Munro and Alasdair Peter Stuart Munro and Sarah Murphy and Vincent J. Munster and Philomena Mweu and Andr{\'e}s No{\'e} and Fay L. Nugent and Elizabeth Nuthall and Katie O'Brien and Daniel O'connor and Blanch{\'e} Oguti and Jennifer L. Oliver and Catarina Oliveira and Peter John O'Reilly and Mairead Osborn and Piper Osborne and Cathy A Owen and Daniel R Owens and Nelly Owino and Mihaela Pacurar and Kaye Parker and Helena Parracho and Maia Patrick-Smith and Victoria Payne and Jennifer Pearce and Yanchun Peng and Marco Polo Peralta {\'A}lvarez and James C Perring and Katja J. Pfafferott and Dimitra Pipini and Emma L Plested and Helen Pluess‐Hall and Katrina M. Pollock and Ian D. Poulton and Laura Presland and Samuel Provstgaard-Morys and David Pulido and Kajal Radia and Fernando Ramos Lopez and Jade Rand and Helen Ratcliffe and Thomas A. Rawlinson and Sarah Rhead and Amy Riddell and Adam John Ritchie and Hannah Roberts and Joanna Robson and Sophie Roche and Cornelius Rohde and Christine S. Rollier and Rossana Romani and Indra Rudiansyah and Stephen Saich and Sara Sajjad and Stephannie Salvador and L{\'i}dia S{\`A}NCHEZ RIERA and Helen Sanders and Katherine Sanders and Shari Sapaun and Chloe Sayce and Ella Schofield and Gavin R. Screaton and Beatrice Selby and Calum Semple and Hannah R. Sharpe and Imam H Shaik and Adam Shea and Holly Shelton and Sarah E. Silk and Laura Silva-Reyes and Donal T. Skelly and Heather Smee and Catherine C. Smith and David J. Smith and Rinn Song and Alexandra J. Spencer and Elizabeth Stafford and Amy E. Steele and Elena Stefanova and Lisa Stockdale and Anna Szigeti and Abdessamad Tahiri-Alaoui and Moira Tait and Helen Talbot and Rachel Tanner and Iona J. Taylor and Victoria Taylor and Rebecca te Water Naude and Nazia Thakur and Yrene Themistocleous and Andreas C. Themistocleous and Merin Thomas and Tonia Thomas and Amber J. Thompson and Samantha Thomson-Hill and Jennifer Tomlins and Susan Tonks and James Towner and Nguyen H. Tran and Julia A. Tree and Adam Truby and Kate Turkentine and Cheryl Turner and Nicola Turner and Sally Turner and Tobias J. Tuthill and Marta Ulaszewska and Rachel Sarah Varughese and Neeltje van Doremalen and Kristin Veighey and Marije K. Verheul and Iason Vichos and Elizabeth Vitale and Laura Walker and Marion E E Watson and Benjamin Welham and J. K. Wheat and Caroline White and Rachel White and Andrew T. Worth and Daniel Wright and Suzie Wright and Xin Li Yao and Yasmine Yau},
  journal={Lancet (London, England)},
  year={2020},
  volume={396},
  pages={467 - 478}
}

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