Safety and immunogenicity of one dose of MenACWY-CRM, an investigational quadrivalent meningococcal glycoconjugate vaccine, when administered to adolescents concomitantly or sequentially with Tdap and HPV vaccines.

@article{Arguedas2010SafetyAI,
  title={Safety and immunogenicity of one dose of MenACWY-CRM, an investigational quadrivalent meningococcal glycoconjugate vaccine, when administered to adolescents concomitantly or sequentially with Tdap and HPV vaccines.},
  author={Adriano G. Arguedas and Carolina Soley and Cecilia Loaiza and Gustavo A. Rincon and Silvia Guevara and Alejandro Alonso P{\'e}rez and Wendy Porras and Oscar Alvarado and Liliana Aguilar and Arturo Abdelnour and Uwe Grunwald and Lisa Bedell and Alessandra Anemona and Peter M. Dull},
  journal={Vaccine},
  year={2010},
  volume={28 18},
  pages={3171-9}
}
This Phase III study evaluates an investigational quadrivalent meningococcal CRM(197) conjugate vaccine, MenACWY-CRM (Novartis Vaccines), when administered concomitantly or sequentially with two other recommended adolescent vaccines; combined tetanus, reduced diphtheria and acellular pertussis (Tdap), and human papillomavirus (HPV) vaccine. In this single-centre study, 1620 subjects 11-18 years of age, were randomized to three groups (1:1:1) to receive MenACWY-CRM concomitantly or sequentially… CONTINUE READING
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