Safety and immunogenicity of modified vaccinia Ankara (ACAM3000): effect of dose and route of administration.

Abstract

BACKGROUND We conducted a clinical trial of the safety and immunogenicity of modified vaccinia Ankara (MVA) to examine the effects of dose and route of administration. METHODS Seventy-two healthy, vaccinia virus-naive subjects received 1 of 6 regimens of MVA (ACAM3000) or placebo consisting of 2 administrations given 1 month apart. RESULTS MVA was… (More)
DOI: 10.1086/651561

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