Safety and immunogenicity of a combined pentavalent diphtheria, tetanus, acellular pertussis, inactivated poliovirus and Haemophilus influenzae type b-tetanus conjugate vaccine in infants, compared with a whole cell pertussis pentavalent vaccine.

@article{Dagan1997SafetyAI,
  title={Safety and immunogenicity of a combined pentavalent diphtheria, tetanus, acellular pertussis, inactivated poliovirus and Haemophilus influenzae type b-tetanus conjugate vaccine in infants, compared with a whole cell pertussis pentavalent vaccine.},
  author={Ron Dagan and K Igbaria and Lolita Piglansky and Rimma Melamed and Paul Willems and Alberto Grossi and Achim Kaufhold},
  journal={The Pediatric infectious disease journal},
  year={1997},
  volume={16 12},
  pages={1113-21}
}
BACKGROUND We compared the safety and immunogenicity of two combined diphtheria-tetanus-pertussis-inactivated poliovirus vaccines containing either acellular (Pa, SmithKline Beecham Biologicals) or whole cell (Pw, Pasteur Merieux Connaught) pertussis components, mixed with a Haemophilus influenzae type b polysaccharide polyribosylribitol phosphate-tetanus conjugate vaccine in an open, randomized study in healthy infants. DESIGN The combined vaccines were given at 2, 4, 6 and 12 months of age… CONTINUE READING
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