Safety and efficient ex vivo expansion of stem cells using platelet-rich plasma technology.

@article{Anitua2013SafetyAE,
  title={Safety and efficient ex vivo expansion of stem cells using platelet-rich plasma technology.},
  author={Eduardo Anitua and R Prado and Gorka Orive},
  journal={Therapeutic delivery},
  year={2013},
  volume={4 9},
  pages={1163-77}
}
The goal of this Review is to provide an overview of the cell culture media supplements used in the ex vivo expansion of stem cells intended for cell therapy. Currently, the gold standard is the culture supplemented with fetal bovine serum, however, their use in cell therapy raises many concerns. The alternatives to its use are presented, ranging from the use of human serum to platelet-rich plasma (PRP), to serum-free media or extracellular matrix components. Finally, various growth factors… CONTINUE READING