Safety and efficacy of vagus nerve stimulation in fibromyalgia: a phase I/II proof of concept trial.

@article{Lange2011SafetyAE,
  title={Safety and efficacy of vagus nerve stimulation in fibromyalgia: a phase I/II proof of concept trial.},
  author={Gudrun Lange and Malvin N. Janal and Allen H. Maniker and Jennifer Fitzgibbons and Malusha M Fobler and Dane B. Cook and Benjamin H. Natelson},
  journal={Pain medicine},
  year={2011},
  volume={12 9},
  pages={1406-13}
}
OBJECTIVE We performed an open-label Phase I/II trial to evaluate the safety and tolerability of vagus nerve stimulation (VNS) in patients with treatment-resistant fibromyalgia (FM) as well as to determine preliminary measures of efficacy in these patients. METHODS Of 14 patients implanted with the VNS stimulator, 12 patients completed the initial 3-month… CONTINUE READING