Safety and efficacy of umbilical cord mesenchymal stem cell therapy in hereditary spinocerebellar ataxia.

@article{Jin2012SafetyAE,
  title={Safety and efficacy of umbilical cord mesenchymal stem cell therapy in hereditary spinocerebellar ataxia.},
  author={Jiali Jin and Zhuo Liu and Zhen-Juan Lu and De-ning Guan and Chong Wang and Zhi-bin Chen and Jun Zhang and Wei-Yun Zhang and Jiatu Wu and Yun Xu},
  journal={Current neurovascular research},
  year={2012},
  volume={10 1},
  pages={
          11-20
        }
}
Hereditary spinocerebellar ataxia (SCA) is a devastating, incurable disease. Stem-cell-based therapies represent new promise for clinical research in neurology. The objectives of this study were to assess the feasibility, efficacy, and potential toxicity of human umbilical cord mesenchymal stem cells (UCMSCs) therapy in patients with SCA. Sixteen genomically diagnosed SCA patients were enrolled and received intravenous and intrathecal infusion of UCMSCs. Clinical, laboratory, and radiographic… CONTINUE READING
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