Safety and efficacy of tramadol in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study.

@article{Safarinejad2006SafetyAE,
  title={Safety and efficacy of tramadol in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study.},
  author={Mohammad Reza Safarinejad and Seyyed Yoosof Hosseini},
  journal={Journal of clinical psychopharmacology},
  year={2006},
  volume={26 1},
  pages={27-31}
}
PURPOSE To evaluate the efficacy and safety of a new serotonergic centrally acting drug tramadol in delaying ejaculation in patients with premature ejaculation. MATERIALS AND METHODS Sixty-four potent men with premature ejaculation were randomly assigned to receive 50 mg tramadol (group 1, n = 32) or placebo (group 2, n = 32) approximately 2 hours before planned sexual activity, for 8 weeks. Pretreatment evaluation included history and physical examination, intravaginal ejaculatory latency… CONTINUE READING
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