Safety and efficacy of total parenteral nutrition versus total enteral nutrition for patients with severe acute pancreatitis: a meta-analysis

@article{Li2018SafetyAE,
  title={Safety and efficacy of total parenteral nutrition versus total enteral nutrition for patients with severe acute pancreatitis: a meta-analysis},
  author={Wen Li and Ji-xi Liu and Shuqiao Zhao and Jingtao Li},
  journal={The Journal of International Medical Research},
  year={2018},
  volume={46},
  pages={3948 - 3958}
}
Objective This study was performed to systematically compare the safety and efficacy of total enteral nutrition (TEN) and total parenteral nutrition (TPN) for patients with severe acute pancreatitis (SAP). Methods The PubMed database was searched up to January 2017, and nine studies were retrieved. These studies were selected according to specific eligibility criteria. The methodological quality of each trial was assessed, and the study design, interventions, participant characteristics, and… Expand
Efficacy comparisons of enteral nutrition and parenteral nutrition in patients with severe acute pancreatitis: a meta-analysis from randomized controlled trials
TLDR
The meta-analysis suggested that EN, but not PN, significantly reduced the risk of mortality, infection, and complications for patients with SAP, and is recommended as an initial treatment option for Patients with SAP. Expand
Early oral vs parenteral nutrition in acute pancreatitis: a retrospective analysis of clinical outcomes and hospital costs from a tertiary care referral center
TLDR
The use of EN in AP is associated with substantial clinical and economic benefits and following AP guidelines is the best way to cure patients and improve healthcare system costs. Expand
Sequential nutrition support with the combination of parenteral and enteral nutrition in the management of severe acute pancreatitis
TLDR
TPN-EN can improve the prognosis of SAP patients and shorten hospital stay without increasing the visceral burdens, and blood glucose control showed no significant difference between these two groups. Expand
Meta-Analysis of Efficacy of Rhubarb Combined With Early Enteral Nutrition for the Treatment of Severe Acute Pancreatitis.
TLDR
Combination of EEN and rhubarb may improve the gastrointestinal function, inhibit systemic inflammation and disease severity, and enhance the efficacy of enteral nutrition, leading to better therapeutic effectiveness in SAP patients. Expand
Nasogastric or nasojejunal feeding in pediatric acute pancreatitis: a randomized controlled trial
  • Hong Zhao, Yan Han, +5 authors J. Lou
  • Medicine
  • World Journal of Pediatrics
  • 2021
TLDR
NG tube feeding appears to be effective and safe for acute pediatric pancreatitis compared with NJ tube feeding, and high qualified, large sample sized, randomized controlled trials in pediatric population are needed. Expand
Nutritional Support in Patients with Severe Acute Pancreatitis-Current Standards
TLDR
The role of parenteral nutrition (PN) in SAP patients is limited to patients in whom EN is not possible or contraindicated, and early versus delayed EN, nasogastric versus nasojejunal tube for EN, EN versus PN in SAP Patients and the role of immunonutrition (IN) are discussed. Expand
Evaluation of Chinese updated guideline for acute pancreatitis on management of moderately severe and severe acute pancreatitis.
TLDR
There was a prominent transition in the management of moderately severe and severe AP after the release of the guideline in China in 2013, which made the prognosis better, and in-hospital case-fatality rates significantly decreased in the Post group. Expand
Modern Approaches to Enteral Nutrition in Intensive Care
The analysis of the literature data allowed us to establish that today enteral nutrition (EN) is unanimously recognized by specialists as the preferred method of nutritional therapy, whichExpand
ESPEN guideline on clinical nutrition in acute and chronic pancreatitis.
TLDR
Patients with chronic pancreatitis should be considered at risk, screened and supplemented accordingly, and osteoporosis and increased facture risk should be acknowledged in patients with chronic pancreas, and preventive measures should be consideration. Expand
Nutrition and Acute Pancreatitis
  • A. Yang
  • Medicine
  • Journal of clinical medicine
  • 2021
TLDR
An overview of the clinical management of nutrition in acute pancreatitis based on the currently available data is provided to correct the negative nitrogen balance to reduce inflammation and improve outcomes. Expand
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TLDR
Enteral nutrition appears safer than total parenteral nutrition in nutrition support of patients with severe acute pancreatitis, and was associated with a significantly lower risk of infections. Expand
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Total enteral nutritional support is associated with lower mortality, fewer infectious complications, decreased organ failure and surgical intervention rate compared to parenteral nutritional support. Expand
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TLDR
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TLDR
There is a trend towards reductions in the adverse outcomes of acute pancreatitis after administration of enteral nutrition, but clearly there is insufficient data to draw firm conclusions about the effectiveness and safety of EN versus TPN. Expand
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Total enteral nutrition is better than total parenteral nutrition in the prevention of pancreatic necrotic infection in severe acute pancreatitis. Expand
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TLDR
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